DSPE-PEG4-NHS ester
DSPE-PEG4-NHS ester
SKU:QM-0012494-01
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Product Details
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Description
DSPE-PEG4-NHS ester is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery[1]. NHS esters can be conjugated to amino acids or other molecules containing an amino group.
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Molecular Formula
C57H105N2O17P
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Molecular Weight
1121.42
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Smiles
O=C(O[C@@H](COP(O)(OCCNC(CCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O)=O)COC(CCCCCCCCCCCCCCCCC)=O)CCCCCCCCCCCCCCCCC
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Target
Biochemical Assay Reagents
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Shipping Conditions
Room temperature
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DSPE-PEG4-NHS ester
DSPE-PEG4-NHS ester is a certified lipid-PEG conjugation reagent supplied by Quantimol for laboratory and scientific research.
This compound is a phospholipid-PEG derivative featuring an NHS (N-hydroxysuccinimide) ester reactive group. It is widely used to form PEGylated micelles and liposomal nanoparticles for drug delivery applications. The NHS ester reacts selectively with primary amines (e.g. lysine residues, amine-functionalised molecules) to form stable amide bonds, enabling bioconjugation of proteins, peptides, antibodies, and small molecules to lipid nanoparticle surfaces.
Key properties:
- Compound class: Lipid-PEG / NHS ester conjugation reagent
- Reactive group: NHS ester (amine-reactive)
- PEG chain: PEG4 (tetraethylene glycol)
- Lipid anchor: DSPE (distearoylphosphoethanolamine)
- Purity: ≥95% (HPLC)
- Storage: -20°C, protected from moisture
- Solubility: DMSO, chloroform, or DMF (recommended)
Applications: Lipid nanoparticle (LNP) surface functionalisation, PEGylated liposome preparation, antibody-lipid conjugation, drug delivery research, bioconjugation chemistry.
Supplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.