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(-) - (E) -Guggulsterone (Standard) [CAS 39025-24-6]

(-) - (E) -Guggulsterone (Standard) [CAS 39025-24-6]

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SKU:QM-0114541-01

£452.17 GBP
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  • Description

    (-) - (E) -guggulsterone (Standard) is the analytical standard for (-) - (E) -guggulsterone ((E) -Guggulsterone). (-) - (E) -Guggulsterone is an orally active natural stereoisomer of Guggulsterone (HY-107738). (-) - (E) -Guggulsterone is an antagonist for the Farnesoid X Receptor (FXR) with an IC50 of 24.06 μM and possesses potent hypolipidemic properties. (-) - (E) -Guggulsterone suppresses dengue virus (DENV) replication by upregulating antiviral interferon responses by inducing HO-1 expression via Nrf2 activation. (-) - (E) -Guggulsterone exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. (-) - (E) -Guggulsterone has cardiac protective and antioxidant activities in rats.

  • CAS Number

    [39025-24-6]

  • Molecular Formula

    C21H28O2

  • Molecular Weight

    312.45

  • Smiles

    C/C=C1C(C[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]/12C)=O)=O

  • Target

    Bacterial; Cytochrome P450; Dengue Virus; Drug Metabolite; Estrogen Receptor/ERR; FXR; Heme Oxygenase (HO) ; Keap1-Nrf2; Reactive Oxygen Species (ROS) ; Reference Standards

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Variant Variant total Quantity Price Variant total
5 mgQM-0114541-01
5 mgQM-0114541-01
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£297.90
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£452.17/ea
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£297.90
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£452.17/ea
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10 mgQM-0114541-02
10 mgQM-0114541-02
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£483.30
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£702.46/ea
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£483.30
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£702.46/ea
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25 mgQM-0114541-03
25 mgQM-0114541-03
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£966.60
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£1,354.91/ea
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£966.60
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£1,354.91/ea
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50 mgQM-0114541-04
50 mgQM-0114541-04
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£1,543.50
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£2,133.72/ea
£0.00
Regular price
£1,543.50
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£2,133.72/ea
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100 mgQM-0114541-05
100 mgQM-0114541-05
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£2,469.60
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£3,383.96/ea
£0.00
Regular price
£2,469.60
Sale price
£3,383.96/ea
£0.00

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(-) - (E) -Guggulsterone (Standard) [CAS 39025-24-6]

(-) - (E) -Guggulsterone (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.