(E/Z) -Icerguastat (hydrochloride) [CAS 32597-86-7]
(E/Z) -Icerguastat (hydrochloride) [CAS 32597-86-7]
SKU:QM-0135815
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Product Details
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Description
(E/Z) -Icerguastat hydrochloride ((E/Z) -Sephin1 hydrochloride) is a selective inhibitor with activity that prolongs the phosphorylation effects of eIF2α. (E/Z) -Icerguastat hydrochloride protects cells from defects in proteostasis. (E/Z) -Icerguastat hydrochloride was shown to significantly extend the survival of infected prion mice in a mouse model. (E/Z) -Icerguastat hydrochloride effectively reduces PrPSc expression and prion sequence activity in various neuronal cell lines persistently infected with different prion strains[1].
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CAS Number
[32597-86-7]
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Molecular Formula
C8H10Cl2N4
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Molecular Weight
233.1
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Smiles
ClC1=CC=CC=C1/C=N/NC(N)=N.Cl
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Target
Phosphatase
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Shipping Conditions
Room temperature
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(E/Z) -Icerguastat (hydrochloride) [CAS 32597-86-7]
(E/Z) -Icerguastat (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.