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EB-47 (dihydrochloride) [CAS 1190332-25-2]
EB-47 (dihydrochloride) [CAS 1190332-25-2]
SKU:QM-0136168-01
£238.32 GBP
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Product Details
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Description
EB-47 dihydrochloride, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM. EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite[1].
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CAS Number
[1190332-25-2]
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Molecular Formula
C24H29Cl2N9O6
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Molecular Weight
610.45
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Smiles
O=C1NCC2=C(C=CC=C21)NC(CN3CCN(CC3)C([C@H]4O[C@H]([C@@H]([C@@H]4O)O)N5C6=C(N=C5)C(N)=NC=N6)=O)=O.[H]Cl.[H]Cl
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Target
PARP
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Purity
99.58
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Solubility
DMSO : 62.5 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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EB-47 (dihydrochloride) [CAS 1190332-25-2]
EB-47 (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.