Ecopipam (hydrochloride) [CAS 190133-94-9]
Ecopipam (hydrochloride) [CAS 190133-94-9]
SKU:QM-0149099-01
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Product Details
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Description
Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively) . Ecopipam hydrochloride can be used for the research of schizophrenia and obesity[1][3].
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CAS Number
[190133-94-9]
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Molecular Formula
C19H21Cl2NO
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Molecular Weight
350.28
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Smiles
OC1=C(Cl)C=C2C([C@]3([H])[C@@](CCC4=C3C=CC=C4)([H])N(C)CC2)=C1.[H]Cl
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Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor
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Isoform
D1 Receptor; D2 Receptor; D4 Receptor; D5 Receptor; MUC4; α adrenergic receptor
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Purity
99.19
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Ecopipam (hydrochloride) [CAS 190133-94-9]
Ecopipam (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.