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EGFR/CDK2-IN-3
EGFR/CDK2-IN-3
SKU:QM-0072217
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Quantity
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Product Details
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Description
EGFR/CDK2-IN-3 (compound 4b) is a dual inhibitor of EGFR and CDK-2 with IC50s of 71.7 and 113.7 nM, respectively. EGFR/CDK2-IN-3 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-3 has significant anti-cancer cell toxicity and inhibits MCF-7 with an IC50 of 3.16 μM[1].
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Molecular Formula
C30H20N6OS
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Molecular Weight
512.58
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Smiles
O=C(C1=CN(C2=CC=CC=C2)N=C1C3=NN4C(SC3)=NN=C4C5=CC=CC=C5)C6=CC=C7C=CC=CC7=C6
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Target
CDK; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR/CDK2-IN-3
EGFR/CDK2-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.