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EGFR/CDK2-IN-4
EGFR/CDK2-IN-4
SKU:QM-0072218
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Product Details
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Description
EGFR/CDK2-IN-4 (compound 4c) is a dual inhibitor of EGFR and CDK-2 with IC50s of 89.6 and 165.4 nM, respectively. EGFR/CDK2-IN-4 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-4 has significant anti-cancer cell toxicity and inhibits MCF-7 with an IC50 of 2.74 μM[1].
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Molecular Formula
C24H16N6OS2
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Molecular Weight
468.55
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Smiles
SC1=NN=C2SCC(C3=NN(C4=CC=CC=C4)C=C3C(C5=CC=C6C=CC=CC6=C5)=O)=NN21
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Target
CDK; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR/CDK2-IN-4
EGFR/CDK2-IN-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.