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EGFR/HER2-IN-10 [CAS 2931499-82-8]
EGFR/HER2-IN-10 [CAS 2931499-82-8]
SKU:QM-0072917
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Product Details
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Description
EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC50s of 2.3 nM and 234 nM for EGFR and HER2, respectively. EGFR/HER2-IN-10 shows an effective antiproliferative action against prostate carcinoma[1].
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CAS Number
[2931499-82-8]
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Molecular Formula
C29H24ClF3N6O5
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Molecular Weight
628.99
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Smiles
O=[N+](C1=NC=CN1CCCCOC2=CC3=C(NC4=CC=C(OC5=CC=CC(C(F)(F)F)=C5)C(Cl)=C4)N=CN=C3C=C2OC)[O-]
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Target
EGFR
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Isoform
EGFR/ErbB1/HER1; ErbB2/HER2
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR/HER2-IN-10 [CAS 2931499-82-8]
EGFR/HER2-IN-10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.