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EGFR/HER2-IN-12 [CAS 2237230-21-4]

EGFR/HER2-IN-12 [CAS 2237230-21-4]

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SKU:QM-0091482

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  • Description

    EGFR/HER2-IN-12 (compound 14b) is a dual inhibitor of EGFR and HER2 with 81% and 51% inhibition at 10 μM. The toxicity of EGFR/HER2-IN-12 to cancer cells A431 and MDA-MB-361 was not significant[1].

  • CAS Number

    [2237230-21-4]

  • Molecular Formula

    C25H17ClN4O3S

  • Molecular Weight

    488.95

  • Smiles

    O=[N+]([O-])C1=CC=C(C2=CC3=C(NC4=CC=C(C(Cl)=C4)OC5=CC=CC(C)=C5)N=CN=C3S2)C=C1

  • Target

    EGFR

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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EGFR/HER2-IN-12 [CAS 2237230-21-4]

EGFR/HER2-IN-12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.