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EGFR/HER2-IN-8 [CAS 2820126-32-5]
EGFR/HER2-IN-8 [CAS 2820126-32-5]
SKU:QM-0069211
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Product Details
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Description
EGFR/HER2-IN-8 (compound 34) is a EGFR/HER2 and DHFR inhibitor. EGFR/HER2-IN-8 inhibits EGFR kinase, HER2 kinase and DHFR with IC50s of 0.45, 0.244 and 5.669 μM, respectively. EGFR/HER2-IN-8 shows anticancer activity against several cancer cell lines with high safety profile and selectivity indices. EGFR/HER2-IN-8 can be used for the research of cancer[1].
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CAS Number
[2820126-32-5]
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Molecular Formula
C16H16N4O2S
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Molecular Weight
328.39
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Smiles
O=C(C1=CSC2=NC=C(C3=CC=C(C)C=C3)N21)NNC(CC)=O
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Target
EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR/HER2-IN-8 [CAS 2820126-32-5]
EGFR/HER2-IN-8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.