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EGFR/HER2/TS-IN-2 [CAS 2444364-04-7]
EGFR/HER2/TS-IN-2 [CAS 2444364-04-7]
SKU:QM-0066711
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Product Details
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Description
EGFR/HER2/TS-IN-2 (compound 17) is a potent EGFR/HER2 and TS (Thymidylate synthase) inhibitor, with IC50 values of 0.173, 0.125, and 1.12 μM, respectively. EGFR/HER2/TS-IN-2 shows cytotoxic activity against MDA-MB-231 cancer cell lines, with an IC50 of 1.69 μM[1].
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CAS Number
[2444364-04-7]
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Molecular Formula
C26H21N7OS2
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Molecular Weight
511.62
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Smiles
N#CC1=C(N2N=C(C)C=C2C)N=C(SCC(NC3=NC4=C(S3)C=C(C)C=C4)=O)N=C1C5=CC=CC=C5
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Target
EGFR; Thymidylate Synthase
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Isoform
EGFR/ErbB1/HER1; ErbB2/HER2
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR/HER2/TS-IN-2 [CAS 2444364-04-7]
EGFR/HER2/TS-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.