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EGFR-IN-107
EGFR-IN-107
SKU:QM-0100594
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Product Details
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Description
EGFR-IN-107 (compound 3r) is an orally active EGFR inhibitor with IC50 values of 0.4333 μM for EGFRWT and 0.0438 μM for EGFRL858R/T790M. EGFR-IN-107 has anti-proliferative activity and can inhibit the proliferation of H1975 cells and induce their apoptosis. EGFR-IN-107 can be used in cancer research[1].
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Molecular Formula
C34H36FN7O2
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Molecular Weight
593.69
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Smiles
C=CC(NC1=C(C=C(C(NC2=NC(C3=C(N(C4=C3C=CC=C4)C)C5=CC=CC(F)=C5)=CC=N2)=C1)OC)N(CCN(C)C)C)=O
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Target
Apoptosis; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-107
EGFR-IN-107 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.