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EGFR-IN-108 (chloride)
EGFR-IN-108 (chloride)
SKU:QM-0128986
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Quantity
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Product Details
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Description
EGFR-IN-108 chloride (Compound Ru3S) is an EGFR inhibitor with an IC50 value of 5.8 nM for hEGFR. EGFR-IN-108 chloride induces apoptosis and has anti-proliferative activity against cancer cells. EGFR-IN-108 chloride also has anti-angiogenic effects[1].
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Molecular Formula
C45H40Cl3F3N8O3Ru
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Molecular Weight
1005.28
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Smiles
CC1=[N]2[Ru+2]3([N]4=C(C)C=CC=C4C5=CC=CC(C)=[N]35)([N]6=CC=C(OC7=CC=C(NC(NC8=CC=C(Cl)C(C(F)(F)F)=C8)=O)C=C7)C=C6C9=O)([NH]9C)[N]%10=C(C)C=CC=C%10C2=CC=C1.[Cl-].[Cl-]
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Target
Apoptosis; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-108 (chloride)
EGFR-IN-108 (chloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.