1
/
of
1
EGFR-IN-109 [CAS 3019971-97-9]
EGFR-IN-109 [CAS 3019971-97-9]
SKU:QM-0117792
Price on request
Quantity
Request quote or documents
![EGFR-IN-109 [CAS 3019971-97-9]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
EGFR-IN-109 (compound 4) is an EGFR inhibitor, with the IC50 values of 25.8 and 182.3 nM for EGFRWT and EGFRT790M, respectively. EGFR-IN-109 arrests the cancer cells’ growth at the G2/M phase and induces both early and late apoptosis. EGFR-IN-109 can be used in cancer research[1].
-
CAS Number
[3019971-97-9]
-
Molecular Formula
C12H16N4OS
-
Molecular Weight
264.35
-
Smiles
NNCC(NC1=O)=NC2=C1C3=C(S2)CC(C)CC3
-
Target
Apoptosis; Bcl-2 Family; Caspase; EGFR
-
Isoform
Bax; Bcl-2; Caspase 3; Caspase 9; EGFR/ErbB1/HER1
-
Solubility
10 mM in DMSO
-
Shipping Conditions
Room temperature
Related Products
- QM-0015916 Wee1/HDAC-IN-1 [CAS 3037071-29-4]
- QM-0013795-01 Vizenpistat [CAS 2687222-58-6]
- QM-0008932 VEGFR-IN-7 [CAS 683235-33-8]
- QM-0008931 VEGFR-IN-6 [CAS 683235-34-9]
- QM-0008885 VEGFR/PDGFR-IN-1 [CAS 342785-98-2]
- QM-0008364-01 Verubecestat (Standard) [CAS 1286770-55-5]
- QM-0007272 Zavondemstat (sodium) [CAS 2908753-07-9]
- QM-0002491-01 Ziritaxestat (Standard) [CAS 1628260-79-6]
- QM-0002017 Zabadinostat (Standard) [CAS 934828-12-3]
- QM-0079654-01 Zabadinostat [CAS 934828-12-3]
Other industry favorites
- QM-0015916 Wee1/HDAC-IN-1 [CAS 3037071-29-4]
- QM-0013795-01 Vizenpistat [CAS 2687222-58-6]
- QM-0154836-01 Verdiperstat [CAS 890655-80-8]
- QM-0142135-01 Virstatin [CAS 88909-96-0]
- QM-0081849-01 Vorinostat (Standard) [CAS 149647-78-9]
- QM-0070505 VEGFR2-IN-3 [CAS 417717-09-0]
- QM-0081529-01 Ziritaxestat [CAS 1628260-79-6]
- QM-0205620-01 VEGFR-3/FLT4, Mouse (HEK293, hFc)
- QM-0178627-01 VinylMyristate (stabilizedwithMEHQ) [CAS 5809-91-6]
- QM-0175073-01 [Nle8] Somatostatin (1-28) (TFA)
EGFR-IN-109 [CAS 3019971-97-9]
EGFR-IN-109 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.