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EGFR-IN-11 [CAS 2463200-44-2]

EGFR-IN-11 [CAS 2463200-44-2]

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QM-0143333-01

£464.31 GBP
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Product Details

  • Description

    EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM for triple mutant EGFRL858R/T790M/C797S. EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis, and arrest cell cycle at G0/G1[1].

  • CAS Number

    [2463200-44-2]

  • Molecular Formula

    C29H35N9O2S

  • Molecular Weight

    573.71

  • Smiles

    CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC4=C(C=N3)N=C(NC5=CC=CC=C5)N4[C@H]6CN(CC6)S(C7CC7)(=O)=O

  • Target

    Apoptosis; EGFR

  • Isoform

    EGFR/ErbB1/HER1

  • Purity

    99.3

  • Solubility

    DMSO : 125 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0143333-01
5 mgQM-0143333-01
£464.31/ea		 £0.00
£464.31/ea £0.00
10 mM - 1 mLQM-0143333-02
10 mM - 1 mLQM-0143333-02
£573.66/ea		 £0.00
£573.66/ea £0.00
10 mgQM-0143333-03
10 mgQM-0143333-03
£715.82/ea		 £0.00
£715.82/ea £0.00
25 mgQM-0143333-04
25 mgQM-0143333-04
£1,166.59/ea		 £0.00
£1,166.59/ea £0.00
50 mgQM-0143333-05
50 mgQM-0143333-05
£1,594.27/ea		 £0.00
£1,594.27/ea £0.00
100 mgQM-0143333-06
100 mgQM-0143333-06
£2,145.88/ea		 £0.00
£2,145.88/ea £0.00
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EGFR-IN-11 [CAS 2463200-44-2]

EGFR-IN-11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.