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EGFR-IN-127
EGFR-IN-127
SKU:QM-0106922
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Product Details
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Description
EGFR-IN-127 is an ATP-competitive EGFR inhibitor with IC50s of 136.3 nM and 161. 2 nM for EGFRdel19 and EGFRdel19/T790M/C797S, respectively. EGFR-IN-127 has the potential for the study of non-small-cell lung cancer (NSCLC) [1].
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Molecular Formula
C24H24FN7O6
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Molecular Weight
525.49
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Smiles
O=C(O)CN(CCN(CC(O)=O)C1)CC(NC2=CC3=C(N=CN=C3NC4=CC(F)=CC=C4)C=C2NC1=O)=O
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Target
EGFR
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Isoform
EGFR/ErbB1/HER1
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Shipping Conditions
Room temperature
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EGFR-IN-127
EGFR-IN-127 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.