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EGFR-IN-141 [CAS 3054263-27-0]
EGFR-IN-141 [CAS 3054263-27-0]
SKU:QM-0009418
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Product Details
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Description
EGFR-IN-141 (Compound 8I) is the inhibitor for EGFR with an IC50 of 2.67 nM. EGFR-IN-141 exhibits cytotoxicity in cancer cell A549 with an IC50 of 13.75 μM. EGFR-IN-141 induces apoptosis and mitochondrial membrane depolarization, and exhibits potential antitumor efficacy[1].
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CAS Number
[3054263-27-0]
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Molecular Formula
C20H15FN8O2S2
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Molecular Weight
482.51
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Smiles
O=C1C2=C(N=CN1CC3=NN=C(N3N)SCC(NC4=NC5=C(S4)C=C(F)C=C5)=O)C=CC=C2
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Target
Apoptosis; EGFR
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Isoform
EGFR/ErbB1/HER1
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Shipping Conditions
Room temperature
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EGFR-IN-141 [CAS 3054263-27-0]
EGFR-IN-141 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.