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EGFR-IN-160 [CAS 2172879-84-2]
EGFR-IN-160 [CAS 2172879-84-2]
SKU:QM-0011681
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Product Details
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Description
EGFR-IN-160 (Compound R12) is an EGFR inhibitor (IC50 values are 1.62, 0.49 and 0.98 μM for EGFRWT, EGFRT790M and EGFRL858R/T790M/C797S, respectively) . EGFR-IN-160 induces G2/M and S phase arrest and apoptosis in NCI-H522 cells, and has anticancer activity. EGFR-IN-160 has antioxidant effects against DPPH (IC50: 12.11 µM) and H2O2 (IC50: 8.89 µM) [1].
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CAS Number
[2172879-84-2]
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Molecular Formula
C15H12N2O4
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Molecular Weight
284.27
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Smiles
COC1=CC(C2=CC(C3=CC=CO3)=NC(O)=N2)=CC=C1O
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Target
EGFR
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Shipping Conditions
Room temperature
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EGFR-IN-160 [CAS 2172879-84-2]
EGFR-IN-160 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.