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EGFR-IN-161 [CAS 3031099-34-7]
EGFR-IN-161 [CAS 3031099-34-7]
SKU:QM-0010946
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Product Details
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Description
EGFR-IN-161 (Compound DD-8) is a potent and reversible inhibitor of L858R/T790M/C797S mutant EGFR kinases, with an IC50 of 0.87 nM. EGFR-IN-161 can induce apoptosis process, G1-phase arrestation, and migration inhibition in tumor cells[1].
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CAS Number
[3031099-34-7]
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Molecular Formula
C33H36Cl2N8O2
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Molecular Weight
647.6
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Smiles
COC1=CC(N(CCN(C)C)C)=C(C=C1NC2=NC(C3=CN(C4=C3C=CC=C4)CCCO)=CC=N2)/N=C/C5=C(C(Cl)=NC=C5)Cl
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Target
Apoptosis; EGFR
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Shipping Conditions
Room temperature
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EGFR-IN-161 [CAS 3031099-34-7]
EGFR-IN-161 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.