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EGFR-IN-164
EGFR-IN-164
SKU:QM-0012416
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Product Details
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Description
EGFR-IN-164 (Compound 4) is a selective and covalent allosteric EGFR inhibitor. EGFR-IN-164 significantly inhibits the activity of EGFRL858R/T790M/C797S kinase (IC50: 48.1 nM) and proliferation of of EGFR-mutant cells. EGFR-IN-164 can be used for drug resistance of cancer research[1].
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Molecular Formula
C23H21FN4O3S2
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Molecular Weight
484.57
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Smiles
C=CS(=O)(C=C)=NC1=CC=CC2=C1CN(C2)C(C3=CC(F)=CC=C3O)C(NC4=NC=CS4)=O
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Target
C-Kit; EGFR
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Shipping Conditions
Room temperature
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EGFR-IN-164
EGFR-IN-164 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.