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EGFR-IN-170
EGFR-IN-170
SKU:QM-0013270
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Product Details
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Description
EGFR-IN-170 (Compound 5c) is an EGFR inhibitor with an IC50 of 5.17 μM. EGFR-IN-170 induces apoptosis by inhibiting Bcl2 expression and activating Bax expression with a significantly increased ratio of Bax/Bcl2. EGFR-IN-170 has potent anticancer activity and inhibits the cell growth of resistant lung cancer cells[1].
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Molecular Formula
C27H27N3O12
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Molecular Weight
585.52
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Smiles
CC(OC[C@H]1O[C@@H]([C@H]([C@H]([C@@H]1OC(C)=O)OC(C)=O)OC(C)=O)N2C=C(N=N2)COC3=CC(C4=CC=CC=C4C3=O)=O)=O
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Target
Apoptosis; Bcl-2 Family; EGFR
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Isoform
Bax; Bcl-2
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Shipping Conditions
Room temperature
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EGFR-IN-170
EGFR-IN-170 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.