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EGFR-IN-171
EGFR-IN-171
SKU:QM-0013290
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Product Details
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Description
EGFR-IN-171 is an EGFR inhibitor with an IC50 value of 0.19 μM. EGFR-IN-171 also inhibits vascular endothelial growth factor 2 (VEGFR-2) with an IC50 value of 31.65 μM. EGFR-IN-171 can induce apoptosis and G2/M phase cell cycle arrest. EGFR-IN-171 can be used for cancer research, such as liver and breast cancer[1].
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Molecular Formula
C32H26N4O3S
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Molecular Weight
546.64
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Smiles
O=C1N(C2=CC=CC=C2)C(SC3=COC(C)=C3C4CC(C5=CC=CO5)NC6=CC=CC=C6N4)=NC7=C1C=CC=C7
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Target
Apoptosis; Bcl-2 Family; EGFR; MDM-2/p53
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Shipping Conditions
Room temperature
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EGFR-IN-171
EGFR-IN-171 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.