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EGFR-IN-174
EGFR-IN-174
SKU:QM-0014911
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Product Details
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Description
EGFR-IN-174 is a potent EGFR inhibitor (IC50 = 0.17 μM) and also displays VEGFR-2 inhibition (IC50 = 0.2007 μM) . EGFR-IN-174 exhibits potent anticancer effects with low cytotoxicity to normal cells. EGFR-IN-174 induces G2/M and Pre-G1 phase arrest and significantly triggers apoptosis. EGFR-IN-174 can be used in cancer research, such as colorectal carcinoma, hepatocellular carcinoma, and breast cancer[1].
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Molecular Formula
C16H23N3O2S3
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Molecular Weight
385.57
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Smiles
S=C(N/N=C(C1=CC=C(S(=O)(N2CCC(C)CC2)=O)C=C1)\C)SC
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Target
Apoptosis; EGFR; VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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EGFR-IN-174
EGFR-IN-174 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.