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EGFR-IN-43 [CAS 3031307-74-8]
EGFR-IN-43 [CAS 3031307-74-8]
SKU:QM-0066386
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Product Details
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Description
EGFR-IN-43 (Compound 17c) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-43 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-43 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-43 has superior anti-cancer activity[1].
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CAS Number
[3031307-74-8]
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Molecular Formula
C50H55ClFN5O5
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Molecular Weight
860.45
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Smiles
ClC1=CC(NC2=C3C(C=C(OC)C(OCCCNC(CCCCCCN(CCOC4=CC=C(C=C4)/C(C5=CC=C(C=C5)O)=C(CC)\C6=CC=CC=C6)C)=O)=C3)=NC=N2)=CC=C1F
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Target
EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-43 [CAS 3031307-74-8]
EGFR-IN-43 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.