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EGFR-IN-44
EGFR-IN-44
SKU:QM-0066406
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Product Details
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Description
EGFR-IN-44 (Compound 6a) is a potent, orally active EGFR tyrosine kinase inhibitor with an IC50 of 4.11 nM. EGFR-IN-44 induces cell apoptosis and shows an oral bioavailability value of 33.57%. EGFR-IN-44 can be studied for non-small-cell lung cancers[1].
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Molecular Formula
C27H29ClN6O2S
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Molecular Weight
537.08
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Smiles
C=CC(NC1=CC(NC2=NC(C3=CSC4=CC=CC=C43)=C(C=N2)Cl)=C(C=C1N(CCN(C)C)C)OC)=O
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Target
Apoptosis; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-44
EGFR-IN-44 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.