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EGFR-IN-52 [CAS 454436-75-0]
EGFR-IN-52 [CAS 454436-75-0]
SKU:QM-0066902
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Product Details
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Description
EGFR-IN-52 (Compound 4) is a potent EGFR inhibitor with IC50 values of 0.358, 86.02 and 432.67 µM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-52 shows cytotoxic activity against cancer cell lines and induces apoptosis[1].
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CAS Number
[454436-75-0]
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Molecular Formula
C19H18N4O3S
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Molecular Weight
382.44
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Smiles
CC1=C(C(N(N1C)C2=CC=CC=C2)=O)NC(NC3=CC=C4OCOC4=C3)=S
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Target
Apoptosis; EGFR
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Isoform
EGFR/ErbB1/HER1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-52 [CAS 454436-75-0]
EGFR-IN-52 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.