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EGFR-IN-59 [CAS 2529891-44-7]
EGFR-IN-59 [CAS 2529891-44-7]
SKU:QM-0067586
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Product Details
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Description
EGFR-IN-59 (Compound 8c) is a EGFR inhibitor (IC50=190 nM) and apoptosis inducer. EGFR-IN-59 exhibits cytotoxicity against non-small lung cancer cell lines (A549) and normal lung fibroblasts (WI38) with IC50s of 8.62 and 52.6 μM, respectively. EGFR-IN-59 can be used for the research of various cancers such as non-small cell lung cancer (NSCLC), head and neck cancer, breast cancer and colorectal cancer[1].
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CAS Number
[2529891-44-7]
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Molecular Formula
C27H23N5O4S
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Molecular Weight
513.57
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Smiles
O=S(C1=CC=C(NC2=C3C=CC=CC3=NC(/C=C/C4=CC=C(OC)C=C4)=N2)C=C1)(NC5=NOC(C)=C5)=O
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Target
Apoptosis; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-59 [CAS 2529891-44-7]
EGFR-IN-59 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.