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EGFR-IN-79
EGFR-IN-79
SKU:QM-0071536
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Product Details
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Description
EGFR-IN-79 (compound 21) is an EGFR inhibior with antitumor activity. EGFR-IN-79 induces ROS-independent apoptosis and EGFR/AKT/mTOR-mediated autophagy. EGFR-IN-79 induces cell death at both proliferating and quiescent zones of EJ28 spheroids. EGFR-IN-79 exhibits safety profile in the zebrafish-based model[1].
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Molecular Formula
C23H16ClN3O3
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Molecular Weight
417.84
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Smiles
ClC1=CC=C(O)C(C2=CC(/C=C/C3=CC=CC([N+]([O-])=O)=C3)=NN2C4=CC=CC=C4)=C1
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Target
EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-79
EGFR-IN-79 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.