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EGFR-IN-81 [CAS 2968419-65-8]
EGFR-IN-81 [CAS 2968419-65-8]
SKU:QM-0071571
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Product Details
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Description
EGFR-IN-81 (Compound 10i) is an EGFR inhibitor. EGFR-IN-81 inhibits EGFR WT and L858R/T790M with IC50s 4.38 nM and 5.69 nM. EGFR-IN-81 has cytotoxic activity against MCF-7 and HCT116 cells with of 2.07 μM and 6.72 μM respectively[1].
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CAS Number
[2968419-65-8]
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Molecular Formula
C28H24F3N5O4
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Molecular Weight
551.52
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Smiles
FC(F)(F)C1=CC=C(NC(C2=CC=C(N(CCC3=CC=C(O)C=C3)C(NC4C(NC(CC4)=O)=O)=N5)C5=C2)=O)C=C1
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Target
EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-81 [CAS 2968419-65-8]
EGFR-IN-81 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.