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EGFR-IN-83
EGFR-IN-83
SKU:QM-0072138
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Product Details
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Description
EGFR-IN-83 (Compound 9) is an EGFR inhibitor (IC50: 2.53 nM) . EGFR-IN-83 has antiproliferative activity against MCF-7 and MDA-MB-231 cells, with IC50 of 2.50 μM and 1.96 μM. EGFR-IN-83 can induce cell apoptosis[1].
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Molecular Formula
C22H17F3N4O
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Molecular Weight
410.39
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Smiles
OCC1=CC=C(NC2=CC3=NC=NC(NC4=CC=CC(C(F)(F)F)=C4)=C3C=C2)C=C1
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Target
Apoptosis; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-83
EGFR-IN-83 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.