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EGFR-IN-89 [CAS 2413029-40-8]
EGFR-IN-89 [CAS 2413029-40-8]
SKU:QM-0076752-01
£652.64 GBP
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Product Details
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Description
EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type[1].
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CAS Number
[2413029-40-8]
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Molecular Formula
C26H31FN8O2S
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Molecular Weight
538.64
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Smiles
FC1=CC(NC2=NC(NC3=C(N(C)S(=O)(C)=O)C=CC=C3)=C4C(NC=C4)=N2)=CC=C1N5CCN(CC)CC5
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Target
EGFR
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Isoform
EGFR/ErbB1/HER1
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Concentration
10mM
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Purity
98.75
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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EGFR-IN-89 [CAS 2413029-40-8]
EGFR-IN-89 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.