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EGFR-IN-92
EGFR-IN-92
SKU:QM-0073293
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Product Details
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Description
EGFR-IN-92 (compound 15) is an allosteric T790M/L858R double mutant EGFR inhibitor. EGFR-IN-92 shows antiproliferative activity against H1975 non-small lung cancer (NSCLC) cancer cells expressing double mutant EGFR[1].
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Molecular Formula
C22H19N3O3
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Molecular Weight
373.4
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Smiles
[O-][N+](C1=CC(NC(C2=C(C)NC3=C2C=CC=C3)C4=C(O)C=CC=C4)=CC=C1)=O
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Target
EGFR
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Isoform
EGFR/ErbB1/HER1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-92
EGFR-IN-92 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.