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EGFR-IN-94
EGFR-IN-94
SKU:QM-0072863
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Product Details
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Description
EGFR-IN-94 (compound 5a) is a EGFR inhibitor with IC50 of 0.086 μM, and also has IC50 of 0.107μM and 2.52 μM for VEGFR-2 and Topo II, respectively. EGFR-IN-94 induces cell apoptosis and arrests cell cycle at the S phase in HepG-2 cells [1].
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Molecular Formula
C19H17ClN8OS
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Molecular Weight
440.91
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Smiles
CC1=C(N=NN1CC2=NC3=CC=CC=C3N2)C(NNC(NC4=CC=C(Cl)C=C4)=S)=O
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Target
Apoptosis; EGFR; VEGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR-IN-94
EGFR-IN-94 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.