EGFR L858R Recombinant Human Active Protein Kinase
EGFR L858R Recombinant Human Active Protein Kinase
SKU:QM-0021047
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Product Details
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Description
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM) . Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR L858R Recombinant Human Active Protein Kinase is a recombinant EGFR L858R protein that can be used to study EGFR L858R-related functions[1].
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Smiles
[EGFRL858RRecombinantHumanActiveProteinKinase]
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Target
EGFR
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Shipping Conditions
Room temperature
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EGFR L858R Recombinant Human Active Protein Kinase
EGFR L858R Recombinant Human Active Protein Kinase is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.