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EGFR T790M/L858R-IN-2 [CAS 2955607-40-4]

EGFR T790M/L858R-IN-2 [CAS 2955607-40-4]

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QM-0076992-01

£325.81 GBP
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Product Details

  • Description

    EGFR T790M/L858R-IN-2 is a potent and selective EGFRT790M/L858R inhibitor with IC50 values of 3.5, 1290 nM for EGFRT790M/L858R, EGFR WT, respectively. EGFR T790M/L858R-IN-2 decreases the expression of p-EGFR, P-AKT, P-ERK1/2. EGFR T790M/L858R-IN-2 induces Apoptosis and cell cycle arrest in the G1 phase. EGFR T790M/L858R-IN-2 shows anti-cancer activity[1].

  • CAS Number

    [2955607-40-4]

  • Molecular Formula

    C28H28FN7O

  • Molecular Weight

    497.57

  • Smiles

    C=CC(NC1=CC=CC(NC2=C3C=C(F)C=CC3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=N2)=C1)=O

  • Target

    Apoptosis; EGFR

  • Isoform

    EGFR/ErbB1/HER1

  • Purity

    99.66

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice
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Variant Variant total Quantity Price Variant total
5 mgQM-0076992-01
5 mgQM-0076992-01
£325.81/ea		 £0.00
£325.81/ea £0.00
10 mM - 1 mLQM-0076992-02
10 mM - 1 mLQM-0076992-02
£352.54/ea		 £0.00
£352.54/ea £0.00
10 mgQM-0076992-03
10 mgQM-0076992-03
£501.98/ea		 £0.00
£501.98/ea £0.00
25 mgQM-0076992-04
25 mgQM-0076992-04
£960.03/ea		 £0.00
£960.03/ea £0.00
50 mgQM-0076992-05
50 mgQM-0076992-05
£1,505.57/ea		 £0.00
£1,505.57/ea £0.00
100 mgQM-0076992-06
100 mgQM-0076992-06
£2,371.86/ea		 £0.00
£2,371.86/ea £0.00
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EGFR T790M/L858R-IN-2 [CAS 2955607-40-4]

EGFR T790M/L858R-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.