EGFR T790M/L858R Recombinant Human Active Protein Kinase
EGFR T790M/L858R Recombinant Human Active Protein Kinase
SKU:QM-0021050
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Product Details
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Description
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM) . Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR T790M/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR T790M/L858R protein that can be used to study EGFR T790M/L858R-related functions[1].
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Smiles
[EGFRT790M/L858RRecombinantHumanActiveProteinKinase]
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Target
EGFR
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Shipping Conditions
Room temperature
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EGFR T790M/L858R Recombinant Human Active Protein Kinase
EGFR T790M/L858R Recombinant Human Active Protein Kinase is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.