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EGFR/VEGFR2-IN-8
EGFR/VEGFR2-IN-8
SKU:QM-0015782
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Product Details
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Description
EGFR/VEGFR2-IN-8 is a dual EGFR/VEGFR-2 inhibitor (EGFR IC50 = 57 nM, VEGFR-2 IC50 = 21 nM) . EGFR/VEGFR2-IN-8 has anti proliferative activity against various tumor cells, such as MCF-7 (IC50 = 20 nM), Panc-1 (IC50 = 22 nM), A-549 (IC50 = 23 nM), HT-29 (IC50 = 23 nM) cells. EGFR/VEGFR2-IN-8 has antioxidant and apoptosis inducing activity. EGFR/VEGFR2-IN-8 can be used for research on various types of cancer[1].
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Molecular Formula
C21H14ClN5O3S
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Molecular Weight
451.89
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Smiles
N#CC1=C(C2=CC=C(OC)C=C2)N=C(SCC3=NC(C4=CC=C(Cl)C=C4)=NO3)NC1=O
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Target
Apoptosis; EGFR; VEGFR
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Shipping Conditions
Room temperature
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EGFR/VEGFR2-IN-8
EGFR/VEGFR2-IN-8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.