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EGFR WT/T790M-IN-2

EGFR WT/T790M-IN-2

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SKU:QM-0096916

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  • Description

    EGFR WT/T790M-IN-2 (Compound 7c) is a EGFR T790M/WT inhibitor with IC50 values of 0.08 and 0.13 μM, respectively. EGFR WT/T790M-IN-2 induces apoptosis by blocking the G0-G1 phase (apoptosis) . EGFR WT/T790M-IN-2 has antitumor activity[1].

  • Molecular Formula

    C19H13ClFN5S

  • Molecular Weight

    397.86

  • Smiles

    N#CC1=C(N=C(N=C1C2=CC=C(F)C=C2)SC)N/N=C/C3=CC(Cl)=CC=C3

  • Target

    Apoptosis; EGFR

  • Isoform

    EGFR/ErbB1/HER1

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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EGFR WT/T790M-IN-2

EGFR WT/T790M-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.