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Elubrixin (hydrochloride) [CAS 688763-65-7]
Elubrixin (hydrochloride) [CAS 688763-65-7]
SKU:QM-0073946
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Product Details
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Description
Elubrixin (SB-656933) hydrochloride is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin hydrochloride inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM) . Elubrixin hydrochloride has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation[1][2][3].
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CAS Number
[688763-65-7]
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Molecular Formula
C17H18Cl3FN4O4S
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Molecular Weight
499.77
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Smiles
O=C(NC1=CC=C(C(S(=O)(N2CCNCC2)=O)=C1O)Cl)NC3=C(Cl)C(F)=CC=C3.Cl
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Target
CXCR; Interleukin Related
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Elubrixin (hydrochloride) [CAS 688763-65-7]
Elubrixin (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.