Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid [CAS 57719-81-0]
Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid [CAS 57719-81-0]
SKU:QM-0165458-01
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Product Details
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Description
Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF) . The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds[1].
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CAS Number
[57719-81-0]
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Molecular Formula
C20H28O4
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Molecular Weight
332.43
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Smiles
O=C1C([C@@]2([H])C[C@]13[C@]([C@@H](O)C2)([H])[C@]4([C@]([C@@](C)(CCC4)C(O)=O)([H])CC3)C)=C
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Target
Tyrosinase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid [CAS 57719-81-0]
Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.