Ethacrynic acid (Standard) [CAS 58-54-8]
Ethacrynic acid (Standard) [CAS 58-54-8]
SKU:QM-0076656-01
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Product Details
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Description
Ethacrynic acid (Standard) is the analytical standard of Ethacrynic acid. This product is intended for research and analytical applications. Ethacrynic acid (Etacrynic acid) is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs) . Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4].
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CAS Number
[58-54-8]
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Molecular Formula
C13H12Cl2O4
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Molecular Weight
303.14
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Smiles
O=C(O)COC1=CC=C(C(C(CC)=C)=O)C(Cl)=C1Cl
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Target
Calcium Channel; Glutathione S-transferase; NF-κB; Reference Standards
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Isoform
L-type calcium channel
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Purity
98.78
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Storage Conditions
4°C, sealed storage, away from light and moisture
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Ethacrynic acid (Standard) [CAS 58-54-8]
Ethacrynic acid (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.