Ethyl 3,4-dihydroxybenzoate (Standard) [CAS 3943-89-3]
Ethyl 3,4-dihydroxybenzoate (Standard) [CAS 3943-89-3]
SKU:QM-0086459-01
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Product Details
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Description
Ethyl 3,4-dihydroxybenzoate (Standard) (Protocatechuic acid ethyl ester (Standard) ) is the analytical standard of Ethyl 3,4-dihydroxybenzoate. This product is intended for research and analytical applications. Ethyl 3,4-dihydroxybenzoate (Protocatechuic acid ethyl ester) is an orally effective, blood-brain barrier-permeable, competitive prolyl hydroxylase (PHD) inhibitor that inhibits the hydroxylation modification of hypoxia-inducible factor (HIF) by PHD. Ethyl 3,4-dihydroxybenzoate stabilizes HIF-1α by inhibiting PHD, activates downstream pathways to induce autophagy and apoptosis of tumor cells, and regulates inflammatory responses, inhibits the NF-κB pathway, improves vascular permeability, and promotes osteoblast differentiation. Ethyl 3,4-dihydroxybenzoate has anti-tumor, anti-hypoxic injury, and bone metabolism regulation effects. It can also be used in the research of cardiovascular protection (such as reducing myocardial ischemic damage), bone tissue engineering (promoting osteogenesis/inhibiting osteoclast differentiation), and prevention and treatment of high-altitude cerebral edema[1][2][3][4].
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CAS Number
[3943-89-3]
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Molecular Formula
C9H10O4
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Molecular Weight
182.18
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Smiles
O=C(OCC)C1=CC=C(O)C(O)=C1
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Target
Apoptosis; Autophagy; HIF/HIF Prolyl-Hydroxylase; NO Synthase; Reactive Oxygen Species (ROS) ; Reference Standards
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Shipping Conditions
Room temperature
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Ethyl 3,4-dihydroxybenzoate (Standard) [CAS 3943-89-3]
Ethyl 3,4-dihydroxybenzoate (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.