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Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol [CAS 2891774-71-1]
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol [CAS 2891774-71-1]
SKU:QM-0101249
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Product Details
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Description
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45) is a camptothecin compound that can inhibit cell proliferation, with an IC50 of 2.92 ng/mL for MDA MB 468 cells. Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol can be used for the research of cancer[1].
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CAS Number
[2891774-71-1]
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Molecular Formula
C31H30FN3O6
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Molecular Weight
559.58
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Smiles
O=C1N2C(C3=NC4=CC(F)=C(C)C(CC5)=C4C([C@H]5NC(C67CC(C6)(C7)CO)=O)=C3C2)=CC([C@](O)8CC)=C1COC8=O
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Target
ADC Payload; Topoisomerase
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Isoform
Camptothecins
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol [CAS 2891774-71-1]
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.