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Exatecan intermediate 10
Exatecan intermediate 10
SKU:QM-0156242-01
£36.91 GBP
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Product Details
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Description
Exatecan intermediate 10 is an intermediate in the synthesis of Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 of 2[1].2 μM (0[1].975 μg/mL) for use in cancer research[1].
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Molecular Formula
C26H24FN3O5
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Molecular Weight
477.48
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Smiles
O=C1OCC(C(N2C(C3=NC4=CC(F)=C(C5=C4C([C@@H](CC5)NC(C)=O)=C3C2)C)=C6)=O)=C6[C@@]1(CC)O
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Target
ADC Payload; Topoisomerase
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Isoform
Camptothecins
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Purity
99.92
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, stored under nitrogen)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Exatecan intermediate 10
Exatecan intermediate 10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.