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Exatecan intermediate 11
Exatecan intermediate 11
SKU:QM-0074376
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Product Details
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Description
Exatecan intermediate 11 is an intermediate for the synthesis of Exatecan. Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM).
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Molecular Formula
C13H13FN2O3
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Molecular Weight
264.25
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Smiles
CC1=C2C(C(/C(CC2)=N\O)=O)=C(NC(C)=O)C=C1F
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Target
ADC Payload; Topoisomerase
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Isoform
Camptothecins
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Exatecan intermediate 11
Exatecan intermediate 11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.