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Exatecan intermediate 8
Exatecan intermediate 8
SKU:QM-0074231
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Product Details
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Description
Exatecan intermediate 8 is an intermediate for the synthesis of Exatecan. Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM).
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Molecular Formula
C30H34FN3O9S
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Molecular Weight
631.67
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Smiles
O=S(C)(O)=O.O=C1[C@@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(OC(C)(C)C)=O)C(C)=C(F)C=C6N=C4C3=C2)=O
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Target
ADC Payload; Topoisomerase
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Isoform
Camptothecins
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Exatecan intermediate 8
Exatecan intermediate 8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.