Fedratinib (Standard) [CAS 936091-26-8]
Fedratinib (Standard) [CAS 936091-26-8]
SKU:QM-0002708-01
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Product Details
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Description
Fedratinib (Standard) is the analytical standard of Fedratinib. This product is intended for research and analytical applications. Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2].
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CAS Number
[936091-26-8]
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Molecular Formula
C27H36N6O3S
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Molecular Weight
524.68
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Smiles
O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)OCCN4CCCC4)=NC=C2C)=C1)(NC(C)(C)C)=O
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Target
Apoptosis; JAK; Reference Standards
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Shipping Conditions
Room temperature
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Fedratinib (Standard) [CAS 936091-26-8]
Fedratinib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.