Flindokalner (Standard) [CAS 187523-35-9]
Flindokalner (Standard) [CAS 187523-35-9]
SKU:QM-0003464-01
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Product Details
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Description
Flindokalner (Standard) is the analytical standard of Flindokalner. This product is intended for research and analytical applications. Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo[1][2].
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CAS Number
[187523-35-9]
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Molecular Formula
C16H10ClF4NO2
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Molecular Weight
359.7
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Smiles
O=C1NC2=C(C=CC(C(F)(F)F)=C2)[C@@]1(C3=CC(Cl)=CC=C3OC)F
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Target
Potassium Channel; Reference Standards
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Shipping Conditions
Room temperature
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Flindokalner (Standard) [CAS 187523-35-9]
Flindokalner (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.