Fonsartan (free acid) [CAS 144628-52-4]
Fonsartan (free acid) [CAS 144628-52-4]
SKU:QM-0088455
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Product Details
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Description
Fonsartan (HOE-720) free acid is an orally active angiotensin II receptor (AT1R) antagonist with an IC50 value of 0.48 nM, exhibiting potent antihypertensive activity. Fonsartan free acid dose-dependently inhibits angiotensin II-induced pressor response in rats (ID50 = 0.11 mg/kg) and shows significant long-lasting blood pressure-lowering effects in high-renin animal models. Fonsartan free acid is primarily used in research on hypertension and cardiovascular diseases[1].
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CAS Number
[144628-52-4]
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Molecular Formula
C26H32N4O5S2
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Molecular Weight
544.69
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Smiles
O=C(C1=C(SC)N=C(CCCC)N1CC2=CC=C(C3=C(S(=O)(NC(NCCC)=O)=O)C=CC=C3)C=C2)O
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Target
Angiotensin Receptor
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Shipping Conditions
Room temperature
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Fonsartan (free acid) [CAS 144628-52-4]
Fonsartan (free acid) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.