Freselestat (quarterhydrate)
Freselestat (quarterhydrate)
SKU:QM-0072447
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Product Details
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Description
Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent and orally active neutrophil elastase inhibitor with a Ki of 12.2 nM. Freselestat quarterhydrate is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat quarterhydrate has a potent anti-inflammatory activity[1][2][3][4].
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Molecular Formula
C23H28N6O4.1/4H2O
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Molecular Weight
457.03
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Smiles
O=C(NC(C(C1=NN=C(C(C)(C)C)O1)=O)C(C)C)CN(C(C2=CC=CC=C2)=NC=C3N)C3=O.[1/4].O
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Target
Elastase
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Purity
99
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Solubility
DMSO : 40 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Freselestat (quarterhydrate)
Freselestat (quarterhydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.